CHEMBL3669498


SMILES O=C1N(Cc2cccc(-n3cccn3)n2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey GDBCAXYOLOFJIR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.76 5.76 5.76 ChEMBL
OX1 OX1R Human Orexin A pKd 5.56 5.56 5.56 ChEMBL
OX2 OX2R Human Orexin A pKd 6.44 6.44 6.44 ChEMBL
OX2 OX2R Human Orexin A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database