CHEMBL3669512


SMILES Cc1noc(-c2cccc(CN3CCCC4(CCN(c5cnc6ccccc6n5)CC4)C3=O)c2)n1
InChIKey YDZDZQBHJHYWCU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.0 6.0 6.0 ChEMBL
OX1 OX1R Human Orexin A pKd 5.34 5.34 5.34 ChEMBL
OX2 OX2R Human Orexin A pKi 6.97 6.97 6.97 ChEMBL
OX2 OX2R Human Orexin A pKd 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database