CHEMBL3669537


SMILES Cn1cc(CN2CCCC3(CCN(c4cnc5ccccc5n4)CC3)C2=O)c2ccccc21
InChIKey NEMITPZPAUHBCI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.38 6.38 6.38 ChEMBL
OX1 OX1R Human Orexin A pKd 5.89 5.89 5.89 ChEMBL
OX2 OX2R Human Orexin A pKi 7.54 7.54 7.54 ChEMBL
OX2 OX2R Human Orexin A pKd 6.87 6.87 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database