CHEMBL3669542


SMILES O=C1CCCC2(CCN(c3nc4cc(Cl)ccc4o3)CC2)N1Cc1cccc2[nH]ccc12
InChIKey FSQNPAXUADPDOQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 448.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.18 6.18 6.18 ChEMBL
OX1 OX1R Human Orexin A pKd 5.85 5.85 5.85 ChEMBL
OX2 OX2R Human Orexin A pKd 7.02 7.02 7.02 ChEMBL
OX2 OX2R Human Orexin A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database