CHEMBL3669549


SMILES Cn1cc(CN2C(=O)CCCC23CCN(c2cnc4ccccc4n2)CC3)c2cccnc21
InChIKey QDAZWKJDVZIOTR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 6.51 6.51 6.51 ChEMBL
OX1 OX1R Human Orexin A pKi 6.13 6.13 6.13 ChEMBL
OX2 OX2R Human Orexin A pKd 7.3 7.3 7.3 ChEMBL
OX2 OX2R Human Orexin A pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database