CHEMBL3669553


SMILES Cc1cnc(-c2cccc(CN3CCCC4(CCN(c5cnc6ccccc6n5)CC4)C3=O)c2)o1
InChIKey MKKQACCARCNABB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.03 7.03 7.03 ChEMBL
OX1 OX1R Human Orexin A pKd 6.64 6.64 6.64 ChEMBL
OX2 OX2R Human Orexin A pKi 8.15 8.15 8.15 ChEMBL
OX2 OX2R Human Orexin A pKd 7.2 7.2 7.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database