CHEMBL3669555


SMILES O=C1N(Cc2ccccc2-c2ccco2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey CXETUYDQSRGNBG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.68 5.68 5.68 ChEMBL
OX1 OX1R Human Orexin A pKi 6.13 6.13 6.13 ChEMBL
OX2 OX2R Human Orexin A pKd 6.73 6.73 6.73 ChEMBL
OX2 OX2R Human Orexin A pKi 7.35 7.35 7.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database