CHEMBL3669564


SMILES O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1ccc3ccccc3n1)CC2
InChIKey KZAXTADHTDIFNK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.24 6.24 6.24 ChEMBL
OX1 OX1R Human Orexin A pKd 6.09 6.09 6.09 ChEMBL
OX2 OX2R Human Orexin A pKd 6.96 6.96 6.96 ChEMBL
OX2 OX2R Human Orexin A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database