CHEMBL3669573


SMILES O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1ncc3ccccc3n1)CC2
InChIKey RSXGQEFCZXHYTD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.01 6.01 6.01 ChEMBL
OX1 OX1R Human Orexin A pKd 6.03 6.03 6.03 ChEMBL
OX2 OX2R Human Orexin A pKd 6.91 6.91 6.91 ChEMBL
OX2 OX2R Human Orexin A pKi 7.16 7.16 7.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database