CHEMBL3669577


SMILES O=C1C(Cc2c[nH]c3ccccc23)NCCC12CCN(c1nccc(-n3cccn3)n1)CC2
InChIKey QZSHBQLZNKETMJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 441.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.59 6.59 6.59 ChEMBL
OX1 OX1R Human Orexin A pKd 6.84 6.84 6.84 ChEMBL
OX2 OX2R Human Orexin A pKi 7.5 7.5 7.5 ChEMBL
OX2 OX2R Human Orexin A pKd 7.39 7.39 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database