CHEMBL3735434


SMILES COc1ccc(OC)c(CCCN(CCc2ccc(OC)c(OC)c2)CCc2ccc3c(c2)OCO3)c1
InChIKey NNXMXZAHWDHMEF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 14
Molecular weight (Da) 507.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 5.1 5.1 5.1 ChEMBL