CHEMBL3670606


SMILES Cc1cc(C)nc(N2CC3CCN(C(=O)c4ccccc4-c4ccccc4)CC32)n1
InChIKey MZDGWJKFCYEWNJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.42 6.09 6.77 ChEMBL
OX2 OX2R Human Orexin A pKi 6.12 7.11 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database