CHEMBL374436


SMILES CCc1cc2c(cc1OC)C(=O)N1CCNC[C@@H]21
InChIKey SWFBKPFOAKNIHM-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.48 7.48 7.48 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.77 7.77 7.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.43 6.43 6.43 ChEMBL