CHEMBL3741292


SMILES O=[N+]([O-])c1ccc(S(=O)(=O)N2CCC(CN3CCC(c4noc5cc(F)ccc45)CC3)CC2)cc1
InChIKey RTIUOKVMNZFXBZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 502.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.78 7.78 7.78 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 5.55 5.55 5.55 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.06 8.06 8.06 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database