LY404039


SMILES N[C@@]1(C(=O)O)CS(=O)(=O)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey AVDUGNCTZRCAHH-MDASVERJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 235.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.04 7.04 7.04 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.83 6.83 6.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu8 GRM8 Human Metabotropic glutamate C pEC50 4.32 4.32 4.32 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.32 7.32 7.32 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.63 7.63 7.63 ChEMBL