DESMOPRESSIN


SMILES N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSCCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
InChIKey NFLWUMRGJYTJIN-NXBWRCJVSA-N

Chemical properties

Hydrogen bond acceptors 15
Hydrogen bond donors 14
Rotatable bonds 19
Molecular weight (Da) 1068.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1B V1BR Rat Vasopressin and oxytocin A pKi 9.7 9.7 9.7 ChEMBL
V1A V1AR Rat Vasopressin and oxytocin A pKi 7.97 7.97 7.97 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKi 9.1 9.1 9.1 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pKi 9.01 9.01 9.01 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pKi 9.43 9.43 9.43 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 8.3 8.3 8.3 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 8.3 8.3 8.3 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database