CHEMBL1085672


SMILES O=C1N(CC2CCCCN2)CCN1c1cccc(Cl)c1
InChIKey HVSRNYNPOUFDNJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 293.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.5 6.5 6.5 ChEMBL
H1 HRH1 Human Histamine A pKi 5.7 5.7 5.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 6.3 6.3 6.3 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.1 6.1 6.1 ChEMBL
D2 DRD2 Human Dopamine A pEC50 9.2 9.2 9.2 ChEMBL