CHEMBL3819567
SMILES | O=C1NCN(c2ccccc2)C12CCN(CCCCc1nc3ccccc3s1)CC2 |
InChIKey | AVKICTLBRHZUTM-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 6 |
Molecular weight (Da) | 420.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 6.2 | 6.2 | 6.2 | ChEMBL |
H1 | HRH1 | Human | Histamine | A | pKi | 6.3 | 7.62 | 8.93 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.88 | 6.88 | 6.88 | ChEMBL |
5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pKi | 6.91 | 6.91 | 6.91 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 7.49 | 7.5 | 7.5 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.71 | 6.71 | 6.71 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 7.62 | 7.62 | 7.62 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |