CHEMBL37170


SMILES Cc1ccc(N2CCN(CC[C@@H]3NC(=O)c4ccccc43)CC2)cc1C
InChIKey WQEPZBNLBWDIRZ-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pKi 7.84 7.84 7.84 ChEMBL
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
α2A ADA2A Rat Adrenoceptors A pKi 6.46 6.46 6.46 ChEMBL
A2B AA2BR Rat Adenosine A pKi 5.77 5.77 5.77 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.11 8.11 8.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database