CHEMBL388123


SMILES Cc1ccccc1C(c1ccccc1)N1CCC(O)(c2ccccc2)CC1
InChIKey GBDUIWBXAKZJPC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 357.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.64 8.5 9.15 ChEMBL
δ OPRD Human Opioid A pKi 5.06 5.79 6.3 ChEMBL
κ OPRK Human Opioid A pKi 5.92 6.18 6.53 ChEMBL
μ OPRM Human Opioid A pKi 6.44 6.84 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.48 7.22 7.64 ChEMBL