CHEMBL373535


SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1
InChIKey AFWQDDUMQAQVSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 267.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.03 6.03 6.03 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.19 7.19 7.19 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.3 7.33 7.4 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.23 6.41 6.5 ChEMBL