CHEMBL3742490


SMILES c1ccc(OCCNC[C@@H]2COC(c3ccccc3)(c3ccccc3)O2)cc1
InChIKey NNVMIQMBTAAZFU-HSZRJFAPSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 8.29 8.29 8.29 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.1 7.1 7.1 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.64 7.64 7.64 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.52 7.52 7.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database