CHEMBL3905247


SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1cc2ccccc2[nH]1
InChIKey KXAOPEMSBPZNPQ-AQYVVDRMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 487.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.12 8.12 8.12 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.19 9.19 9.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 10.54 10.54 10.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.37 9.37 9.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database