CHEMBL3752085


SMILES CN1CCN(c2cc(-c3ccccc3)nc(NCc3ccccc3)n2)CC1
InChIKey NIACEGZKGSHPHM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 359.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.02 6.02 6.02 ChEMBL
H2 HRH2 Human Histamine A pKi 4.99 4.99 4.99 ChEMBL
H1 HRH1 Human Histamine A pKi 5.95 5.95 5.95 ChEMBL
H3 HRH3 Human Histamine A pKi 5.6 5.6 5.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 6.04 6.04 6.04 ChEMBL