Biased Signaling Atlas

MIDODRINE

Agent/drug
Bioactivity

MIDODRINE

SMILES	COc1ccc(OC)c(C(O)CNC(=O)CN)c1
InChIKey	PTKSEFOSCHHMPD-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	3
Rotatable bonds	6
Molecular weight (Da)	254.1

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

MIDODRINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 6

Phase II 5

Phase III 12

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Ascites, unspecified	ME04.Z		0.259	3	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Essential hypertension, unspecified	BA00.Z		0.444	2	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Hepatopulmonary syndrome	DB99.4		0.037	1	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Hypotension, unspecified	BA2Z		0.603	3	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Orthostatic hypotension	BA21		0.583	4	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Sepsis with septic shock	1G41		0.590	3	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Sepsis without septic shock	1G40		0.593	1	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Ascites, unspecified	ME04.Z		0.259	3	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Essential hypertension, unspecified	BA00.Z		0.439	2	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Hepatopulmonary syndrome	DB99.4		0.037	1	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Hypotension, unspecified	BA2Z		0.603	3	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Orthostatic hypotension	BA21		0.583	4	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Sepsis with septic shock	1G41		0.590	3	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Sepsis without septic shock	1G40		0.597	1	Yes
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Ascites, unspecified	ME04.Z		0.259	3	Yes
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Essential hypertension, unspecified	BA00.Z		0.446	2	Yes
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Hepatopulmonary syndrome	DB99.4		0.037	1	Yes
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Hypotension, unspecified	BA2Z		0.603	3	Yes
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Injury of spinal cord, level unspecified	ND51.2		0.003	3	Yes
ADA1D	α_1D-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Orthostatic hypotension	BA21		0.592	4	Yes

Showing 1 to 20 of 22 entries

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MIDODRINE

MIDODRINE

Chemical Properties

Database connections

No bioactivity data available.

MIDODRINE

Drug properties

Clinical Trials

Database connections

Sankey plot

Drug Information