CHEMBL1089040


SMILES CN[C@@H]1CCN(c2nc(N)nc3c2CCCC(c2ccccc2)C3)C1
InChIKey ILOMBVURTLNCEQ-OEMAIJDKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 337.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pKi 8.49 8.49 8.49 ChEMBL
H3 HRH3 Rat Histamine A pKi 6.98 6.98 6.98 ChEMBL
H4 HRH4 Human Histamine A pKi 7.31 7.31 7.31 ChEMBL
H3 HRH3 Human Histamine A pKi 6.65 6.65 6.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database