CHEMBL378515


SMILES COc1ccccc1N1CCN(Cc2cn3nc(Cl)ccc3n2)CC1
InChIKey GSYFEKZSWFXBAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 357.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.47 5.47 5.47 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.11 5.11 5.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.8 8.8 8.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.02 7.06 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database