CHEMBL392437
SMILES | C#Cc1cccc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1 |
InChIKey | UTCVZDGBUSLXBQ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 7 |
Molecular weight (Da) | 429.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Pig | Dopamine | A | pKi | 6.14 | 6.14 | 6.14 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.4 | 7.4 | 7.4 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 9.08 | 9.08 | 9.08 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 7.62 | 7.72 | 7.82 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D3 | DRD3 | Human | Dopamine | A | pEC50 | 8.46 | 8.46 | 8.46 | ChEMBL |