CHEMBL380287


SMILES CN1CCN(c2ccc3nc(CN4CCN(c5ccc(Cl)c(Cl)c5)CC4)cn3n2)CC1
InChIKey VSESOHHTOBROFA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 459.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.1 5.11 5.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database