CHEMBL380464


SMILES CN1CCc2ccccc2Cc2c(ccc(O)c2Cl)CC1
InChIKey UBVTUPXDRIQNKR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 301.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 8.8 8.91 9.01 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.17 8.75 9.34 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.73 8.73 8.73 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.0 9.45 9.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database