CHEMBL3804906


SMILES CN/C(=N\C#N)NC[C@H]1CC[C@H](c2c[nH]cn2)C1
InChIKey WYMMYOFAUJTQKL-UWVGGRQHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 246.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.62 6.81 7.01 ChEMBL
H3 HRH3 Human Histamine A pKi 6.02 6.05 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 6.27 6.27 6.27 ChEMBL
H4 HRH4 Human Histamine A pEC50 6.69 6.96 7.2 ChEMBL
H3 HRH3 Human Histamine A pEC50 6.0 6.21 6.43 ChEMBL