CHEMBL3899169


SMILES Cc1ccc2c(c1)Oc1sc(Cl)cc1C(N1CCN(CC(C)(C)C(=O)O)CC1)=N2
InChIKey PSYAJOBNPBYKRW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 433.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.48 6.67 6.86 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.15 8.31 8.47 ChEMBL
H1 HRH1 Human Histamine A pKi 7.23 7.46 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database