CHEMBL3900245


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cc(F)ccc2F)cc1
InChIKey HNZZMMKIJHPUAD-WIPJZLDNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.44 5.67 5.89 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.34 7.32 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pEC50 5.22 5.22 5.22 ChEMBL
EP2 PE2R2 Human Prostanoid A pEC50 6.9 7.45 8.0 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.75 8.72 9.7 ChEMBL