CHEMBL1093180


SMILES CN1CCN(c2ncnc3c2oc2ccc(Cl)cc23)CC1
InChIKey VUWKQWOFKSEXGA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 302.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.72 8.12 8.33 ChEMBL
H4 HRH4 Human Histamine A pKd 8.2 8.2 8.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 7.72 7.72 7.72 ChEMBL