CHEMBL3968272


SMILES Cc1ncccc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(C(F)(F)F)cc3)C2)n1C
InChIKey MJUZYNLBBPDZMI-QPPBQGQZSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 487.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.91 5.91 5.91 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.78 5.78 5.78 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.48 8.48 8.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.83 5.83 5.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database