CHEMBL3974652
SMILES | O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(F)c2)cc1 |
InChIKey | FVIFTCKGAKHIMG-FSKZSRKQSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 8 |
Molecular weight (Da) | 396.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
EP2 | PE2R2 | Human | Prostanoid | A | pKi | 5.47 | 5.61 | 5.75 | ChEMBL |
EP4 | PE2R4 | Human | Prostanoid | A | pKi | 7.4 | 8.05 | 8.7 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
EP2 | PE2R2 | Human | Prostanoid | A | pEC50 | 7.11 | 7.55 | 8.0 | ChEMBL |
EP3 | PE2R3 | Human | Prostanoid | A | pEC50 | 5.43 | 5.43 | 5.43 | ChEMBL |
EP4 | PE2R4 | Human | Prostanoid | A | pEC50 | 9.0 | 9.7 | 10.4 | ChEMBL |
TP | TA2R | Human | Prostanoid | A | pEC50 | 5.14 | 5.14 | 5.14 | ChEMBL |