CHEMBL3922456


SMILES Cn1cc(C(=O)N2[C@H]3CC[C@@H]2C[C@H]3COc2ccccn2)c(-c2ccccc2)n1
InChIKey YVPZCTKMAKXJOL-NSHGMRRFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 388.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 6.38 6.38 6.38 ChEMBL
OX2 OX2R Human Orexin A pKi 5.51 5.51 5.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database