CHEMBL121744


SMILES COc1ccccc1N1CCN(CC2CC(=O)c3c([nH]c4ccccc34)C2)CC1
InChIKey IHQJQJGQVPNKSI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.8 6.8 6.8 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.81 5.81 5.81 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database