CHEMBL392573
SMILES | Cc1cc2ncc(-c3ccc4cc(CCN5CCC[C@H]5C)ccc4n3)c(C)n2n1 |
InChIKey | NJPWXCCVGLUPFM-QGZVFWFLSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 385.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pKi | 9.03 | 9.03 | 9.04 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 9.62 | 9.62 | 9.62 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pEC50 | 8.3 | 8.3 | 8.3 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pEC50 | 8.95 | 8.95 | 8.95 | ChEMBL |