BURIMAMIDE


SMILES C/N=C(\S)NCCCCc1c[nH]cn1
InChIKey HXRBAVXGYZUSED-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 212.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.16 7.16 7.16 ChEMBL
H4 HRH4 Human Histamine A pKi 6.75 7.08 7.4 ChEMBL
H2 HRH2 Human Histamine A pKi 5.4 5.4 5.4 ChEMBL
H2 HRH2 Human Histamine A pKd 5.11 5.11 5.11 ChEMBL
H3 HRH3 Human Histamine A pKi 7.08 7.08 7.08 ChEMBL
H3 HRH3 Human Histamine A pKd 7.0 7.0 7.0 ChEMBL
H3 HRH3 Rat Histamine A pKi 6.66 7.02 7.32 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
H3 HRH3 Human Histamine A pKi 7.08 7.29 7.9 PDSP Ki database
H4 HRH4 Human Histamine A pKi 6.74 7.07 7.4 PDSP Ki database
H2 HRH2 Human Histamine A pKi 5.4 6.4 7.4 PDSP Ki database
H3 HRH3 Guinea pig Histamine A pKd 7.0 7.0 7.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.7 7.7 7.7 ChEMBL