CHEMBL393581
SMILES | Cc1c(-c2ccc3cc(CCN4CCC[C@H]4C)ccc3n2)cnn1-c1ccccn1 |
InChIKey | TVAWFBREUZKKRV-GOSISDBHSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 5 |
Molecular weight (Da) | 397.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pKi | 8.15 | 8.82 | 9.04 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 9.59 | 9.59 | 9.59 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pEC50 | 8.44 | 8.44 | 8.44 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pEC50 | 8.85 | 8.85 | 8.85 | ChEMBL |