CHEMBL4063336


SMILES N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccc(F)cc2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey YLOYRSFMNLQTKN-DMZJWBPISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 322.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 8.36 8.36 8.36 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 8.18 8.18 8.18 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.72 7.72 7.72 ChEMBL