AMPHETAMINE


SMILES CC(N)Cc1ccccc1
InChIKey KWTSXDURSIMDCE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 135.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 5.27 5.27 5.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.89 4.89 4.89 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 4.89 4.89 4.89 PDSP Ki database
TA1 TAAR1 Rat Trace amine A pKi 6.64 6.64 6.64 PDSP Ki database
TA1 TAAR1 Mouse Trace amine A pKi 7.05 7.05 7.05 PDSP Ki database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 8.28 8.28 8.28 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pEC50 8.21 8.21 8.21 Drug Central