CHEMBL394473


SMILES C#Cc1cccc(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1
InChIKey ZXMMZWMGSDPKNA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 401.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.35 9.35 9.35 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.3 7.3 7.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 7.0 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database