CHEMBL3947221


SMILES N[C@@]1(C(=O)O)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O
InChIKey WNOZOUHFGZKGNT-ANYOLZDRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 375.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 5.72 5.72 5.72 ChEMBL
mGlu6 GRM6 Human Metabotropic glutamate C pIC50 5.48 5.48 5.48 ChEMBL
mGlu7 GRM7 Human Metabotropic glutamate C pIC50 4.98 4.98 4.98 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 7.34 7.34 7.34 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 7.34 7.34 7.34 ChEMBL