CHEMBL4090568


SMILES O=C1COc2ccccc2N1CCCN1CCN(c2nsc3ccccc23)CC1
InChIKey FQGGNELGQIQAHB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MCH1 MCHR1 Human Melanin-concentrating hormone A pEC50 5.98 5.98 5.98 ChEMBL
MCH1 MCHR1 Human Melanin-concentrating hormone A pIC50 5.38 5.38 5.38 ChEMBL