CHEMBL411112


SMILES N#Cc1c(C(=O)NCc2ccc(Cl)c(Cl)c2)nn(-c2ccccc2)c1-n1cccc1
InChIKey QILUOVIHJROTFV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 435.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 6.55 6.55 6.55 PDSP Ki database
CB1 CNR1 Human Cannabinoid A pKi 6.55 6.55 6.55 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 5.4 5.4 5.4 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.41 5.41 5.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pIC50 6.3 6.3 6.3 ChEMBL
CB2 CNR2 Human Cannabinoid A pIC50 5.3 5.3 5.3 ChEMBL