FAUC213
SMILES | Clc1ccc(cc1)N1CCN(CC1)Cc1cc2n(n1)cccc2 |
InChIKey | DTRXURJDKOYCCD-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 3 |
Molecular weight (Da) | 326.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Rat | Dopamine | A | pKi | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 5.26 | 5.26 | 5.26 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 8.17 | 8.58 | 8.66 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 5.26 | 5.26 | 5.26 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 4.92 | 5.56 | 7.34 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 4.33 | 5.37 | 5.88 | ChEMBL |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.26 | 5.26 | 5.26 | ChEMBL |
5-HT2A | 5HT2A | Pig | 5-Hydroxytryptamine | A | pKi | 6.05 | 6.05 | 6.05 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pEC50 | 6.81 | 6.81 | 6.81 | ChEMBL |