CHEMBL401745


SMILES COc1cc(Cl)c(C)c2c1N=C(N)NC2C
InChIKey VZZRHPWRULQIJU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 239.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.33 8.33 8.33 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.84 6.84 6.84 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.6 8.6 8.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database