CHEMBL111749


SMILES CNc1cc(OC)c(C(=O)N[C@H]2CN(Cc3ccccc3)C[C@@H]2C)cc1Cl
InChIKey DCJWAUUNGWWIFD-LIRRHRJNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.37 8.74 9.11 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.66 7.12 7.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.68 7.79 7.96 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.92 5.1 5.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database